Lung Transplantation
It relies on the National Key Clinical Specialty of Thoracic Surgery and the Shanghai Lung Transplantation Engineering Technology Research Center; it is one of the earliest centers in China to carry out clinical research on lung transplantation, and the only transplant center in China that can perform all types of lung transplantation surgery; it has established a complete MDT system for end-stage lung disease preoperative assessment, donor lung repair, transplantation surgery, perioperative ECMO support, and long-term anti-rejection follow-up; and it benchmarks itself against the Lung Transplantation Center of Toronto General Hospital in Canada.
It is affiliated with the National Key Clinical Specialty of Thoracic Surgery and the Shanghai Lung Transplantation Engineering Technology Research Center; one of the earliest lung transplant centers in China, with the largest lung transplant volume in Shanghai; the only transplant center in China capable of performing all lung transplant procedures; a national-level referral platform for end-stage lung diseases; and benchmarked against top international lung transplant centers (Lung Transplant Center of Toronto General Hospital, Canada, and Cleveland Clinic, USA).
Historical Origins and Spiritual Inheritance:
The Pulmonary Hospital initiated animal experiments on lung transplantation in 1978; completed its first clinical lung transplant in 2003; and, through the continuous efforts of three generations of academic leaders—Ding Jia'an, Jiang Gening, and Chen Chang—and upholding the hospital motto of "high moral character, excellent medical skills, and saving lives," has overcome core challenges such as lung transplantation infection, ischemia-reperfusion injury, and acute and chronic rejection, achieving landmark results such as Asia's first lung retransplantation and China's first living donor lung lobe transplantation.
Core business operational efficiency:
The hospital has established an independent lung transplant ward and a dedicated transplant ICU; it performs approximately 40-50 lung transplants annually, with a cumulative total of over 300; it accounts for more than 80% of Shanghai's lung transplant surgeries; its surgical success rate is >99%, and its 5-year postoperative survival rate is higher than the national average and close to international advanced levels; it has established a complete multidisciplinary team (MDT) system encompassing donor lung assessment, organ transport, transplant surgery, perioperative ECMO/CRRT support, and postoperative immunosuppression and lifelong follow-up; it undertakes all types of end-stage lung disease patients awaiting transplantation, post-transplant complications, and referrals for re-lung transplantation from across the country.
Core Advantages: The only domestic company to fully cover all lung transplant procedures; the first in China to perform EVLP ex vivo donor lung repair, ECMO bridging lung transplantation, and cross-hospital ECMO patient transfer and transplantation; independently developed a portable constant-temperature donor lung transport system to extend the preservation time of donor lungs; the MDT team includes a fixed multidisciplinary team of thoracic surgery, respiratory critical care, pulmonary circulation, anesthesia, imaging, pathology, infectious diseases, and transplant immunology. Discipline Positioning and Global Benchmarking: A domestic center for clinical diagnosis, quality control, and translational medicine in lung transplantation for end-stage lung disease; benchmarking against the Lung Transplant Center at Toronto General Hospital in Canada; differentiating itself from overseas centers by focusing on basic immunology research, while pulmonology lung transplantation emphasizes stratification of lung transplantation indications for end-stage lung disease in the Chinese population, EVLP repair of marginal donor lungs, ECMO bridging transplantation for critically ill patients, and integrated prevention and control programs for post-transplant rejection and infection.
Hospital Specialists
8
Lü Fanzhen
Chief Physician, Key Member of Lung Transplant Surgery Team
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Ding Jia'an
Chief Physician, Professor, Founder of Lung Transplantation
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Zhu Yuming
Chief Physician, Professor, Doctoral Supervisor, Head of the Lung Tumor Surgery Subspecialty
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Xie Dong
Chief Physician, Professor, and a key expert in lung transplantation at the Department of Thoracic Surgery, Shanghai Pulmonary Hospital.
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Zhou Min
Chief Physician, Professor, Doctoral Supervisor, Department of Respiratory and Critical Care Medicine, Head of Lung Transplant MDT (Internal Medicine Department)
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Jiang Gening
Chief Physician, Dr., Doctoral Supervisor , Chief Expert, Academic Leader, and Director of the Department of Thoracic Surgery at Shanghai Pulmonary Hospital
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Chen Chang
Chief Physician, Dr., Doctoral Supervisor, President of Shanghai Pulmonary Hospital, Director of Shanghai Lung Transplantation Engineering Technology Research Center
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Zhao Deping
Chief Physician, MD, PhD Supervisor, Administrative Director of Thoracic Surgery and Executive Director of the Lung Transplantation Center at Shanghai Pulmonary Hospital
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